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| 2PN Embryo - 16-18 hours old - the male and female DNA pronuclei are next to each other in the center of the embryo. |
12 embryos might sound like A LOT of babies to some of you out there but I was reading up on 2PN embryos and learned a few things: 2PN stands for "pronuclear" which means that the egg has been fertilized for 18 hours and is a single cell with two pronuclei. (One pronuclei has the male DNA and other other with the female DNA which has not fused together yet.) This is much different than our first match where the embryos were 5 days old at the blastocyst stage. When our 2PN embryos are thawed they will have to grow for a few days in a petri dish before they can be transferred to my body. I read that roughly 30% of 2PN embryos make it to the blastocyst stage so it will be interesting to talk to Dr. K and see if he wants to do a 3 day embryo transfer or a 5 day blastocyst transfer. It seems like there will be more decision making with a group of 2PN embryos than our last transfer with 5 day blasts. You know. . . you think you know about "baby making" and then you read up on embryos, pronuclei, blasts, etc. and you really realize what a miracle a baby is. I am glad we have Dr. K to help us through all of this. He is great at explaining things and always draws funny diagrams to go along with his explanations.
Let's hope that our adoption of these 12 embryos goes quickly and smoothly! Happy New Year everyone!
6 comments:
I hope things fall into place really soon and you are able to schedule your next FET!
Our first FET we transferred three 5-day-old blastocysts and got a BFN. Our second FET we transferred three 2PN and got a BFP - expecting our baby boy February 13! So while the odds are a tad lower, it CAN happen :) Praying that things start moving and that you are able to schedule your second FET sooner than later....
So exciting!! Just so you know, ours were pre-blasts who were transferred. They were very close to blasts. I am VERY excited to see what 2011 brings for the Shacks!
Hi E, I feel so out of touch; I have been unable to view your blog for a couple months! (computer issues...) Anyhoo, just wanted to send my best wishes for a great 2011. I continue to pray for your adoption and be inspired by your approach to everything. Much love, Anna
ohhhhh, the science teacher in me is LOVING all this details! More info anytime :)
And praying that all is going well and speedy as possible.
Love.
the Leggetts
"I read that roughly 30% of 2PN embryos make it to the blastocyst stage so it will be interesting to talk to Dr. K and see if he wants to do a 3 day embryo transfer or a 5 day blastocyst transfer."
I have 2PN embryos, and I hope that this fact doesn't discourage you at all! In light of my experience, and the facts at hand, I'd push for transferring three right off the bat if I knew then what I know now. As far as the decision to to a day 3 or 5 transfer, that decision was always made by my doc. When suggested that we might try to grow them to blasts, he explained, "We have seen no higher success rates with transferring blasts. We prefer to have them in your uterus, where to conditions are ideal, versus in the lab. Some embryos who would do fine in utero, might actually arrest in the lab trying to grow into blasts." I just had to trust his experience and expertise and go with what he thought was best. This really does vary between clinics.
Good luck! Thanks for sharing that link! Even though I have been through all of this several times, I have so much to learn!
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